Do you have proof that she said that?
Would it change anything? Its not a quote I made up, and is a commonly known one. The reason for the Nazi like decree by Isabella was given as BETTER TO DESTROY THEIR BODIES THEREBY GIVING THEM SALVATION FOR THEIR SOULS. Gee thanks - same to you too! European Christianity should be made mandatory teaching in all history classes.
The Spanish Expulsion, 1492
In the same month in which their Majesties [Ferdinand and Isabella] issued the edict that all Jews should be driven out of the kingdom and its territories, in the same month they gave me the order to undertake with sufficient men my expedition of discovery to the Indies." So begins Christopher Columbus's diary. The expulsion that Columbus refers to was so cataclysmic an event that ever since, the date 1492 has been almost as important in Jewish history as in American history. On July 30 of that year, the entire Jewish community, some 200,000 people, were expelled from Spain.
Tens of thousands of refugees died while trying to reach safety. In some instances, Spanish ship captains charged Jewish passengers exorbitant sums, then dumped them overboard in the middle of the ocean. In the last days before the expulsion, rumors spread throughout Spain that the fleeing refugees had swallowed gold and diamonds, and many Jews were knifed to death by brigands hoping to find treasures in their stomachs.
The Jews' expulsion had been the pet project of the Spanish Inquisition, headed by Father Tomas de Torquemada. With their most important project, the country's unification, accomplished, the king and queen concluded that the Jews were expendable. On March 30, they issued the expulsion decree, the order to take effect in precisely four months. The short time span was a great boon to the rest of Spain, as the Jews were forced to liquidate their homes and businesses at absurdly low prices. Throughout those frantic months, Dominican priests actively encouraged Jews to convert to Christianity and thereby gain salvation both in this world and the next.
http://www.jewishvirtuallibrary.org/jsource/Judaism/expulsion.html