For instance, I am aware if it is intelligent life, you may think about looking for mining operations on asteroid belts. But in all my years, I think this is the only method of finding aliens I am aware about. Starships maybe? If so, what about all the life which hasn't managed to make it into the deep of space yet? They will go unnoticed surely?
No, life would change a planet.
Besides, for the purposes of this thread, if they haven't made it to deep space then they haven't made it here obviously.