Laws for the idiots (the "conceivers") apply to them, not their offspring (the aforetomentioned "conceived"). In parallel, should we not enforce rape laws? Such legislation actually also applies to the "conceivers" rather than the "conceived".
I do not imply that inbred human offspring should be killed, and actually am opposed to such, within the bounds of reason.
You have, however, missed my argument concerning percentages. 3% is merely a mean increase and specifies only generally the incidence of deleterious and detrimental mutations. I have yet to see a specification on the incidence of maladaptive mutation in humans (not working in humans, I am little involved in their genetics other than as an end-user) but would be surprised to see that it was 1.3%. This number, I might add, does not translate into concentration of deleterious/detrimental alleles via inbreeding, as it is based on genome-wide substitution/deletion/addition rather than assortative breeding.) Each human alive carries, as I recall, 6-8 deleterious mutations, though not all the same ones. So the incidental consequences to any particular offspring stand to be quite severe, ranging from death to permanent disability. I note also that no study to my knowledge has ever quantified early abortion or embryonic loss due to inbreeding in humans, suggesting strongly that any current impression of impact from this behaviour is highly underestimated.
Actually, from my numbers, the assumption of zero background inbreeding (Fis=0) means <i>no</i> inherent risk for general mating, but nonzero risk for "cousin-lovin". If you care to take such risk, I cannot stop you, but being nonzero it is inherently unnecessary. I similarly cannot compel you to put your seatbelt on every day, and you might well argue that you will never need it since the chances of your ever being in a serious accident are probably about 3-5%. Of course, if you were in a serious accident, you'd probably well regret not wearing it. Your behaviour would be considered: "reckless".
So, if you wish to marry your cousin, go ahead - just don't expect my society to pay your kids' medical bills for genetic disease.
If such a couple were screened for deleterious genes then presumably such marriage would be permissible - however, it would also create precedent and would be in itself overly introspective and societally dangerous. Have we any real desire to see tribal systems like the ones that rage in Iraq, Iran, Syria, Pakistan and Saudi Arabia?
I add further that no religious system currently permiting such marriage provides liturgical methodology for genetic screening. This is also "reckless".
Geoff
I do not imply that inbred human offspring should be killed, and actually am opposed to such, within the bounds of reason.
You have, however, missed my argument concerning percentages. 3% is merely a mean increase and specifies only generally the incidence of deleterious and detrimental mutations. I have yet to see a specification on the incidence of maladaptive mutation in humans (not working in humans, I am little involved in their genetics other than as an end-user) but would be surprised to see that it was 1.3%. This number, I might add, does not translate into concentration of deleterious/detrimental alleles via inbreeding, as it is based on genome-wide substitution/deletion/addition rather than assortative breeding.) Each human alive carries, as I recall, 6-8 deleterious mutations, though not all the same ones. So the incidental consequences to any particular offspring stand to be quite severe, ranging from death to permanent disability. I note also that no study to my knowledge has ever quantified early abortion or embryonic loss due to inbreeding in humans, suggesting strongly that any current impression of impact from this behaviour is highly underestimated.
Actually, from my numbers, the assumption of zero background inbreeding (Fis=0) means <i>no</i> inherent risk for general mating, but nonzero risk for "cousin-lovin". If you care to take such risk, I cannot stop you, but being nonzero it is inherently unnecessary. I similarly cannot compel you to put your seatbelt on every day, and you might well argue that you will never need it since the chances of your ever being in a serious accident are probably about 3-5%. Of course, if you were in a serious accident, you'd probably well regret not wearing it. Your behaviour would be considered: "reckless".
So, if you wish to marry your cousin, go ahead - just don't expect my society to pay your kids' medical bills for genetic disease.
If such a couple were screened for deleterious genes then presumably such marriage would be permissible - however, it would also create precedent and would be in itself overly introspective and societally dangerous. Have we any real desire to see tribal systems like the ones that rage in Iraq, Iran, Syria, Pakistan and Saudi Arabia?
I add further that no religious system currently permiting such marriage provides liturgical methodology for genetic screening. This is also "reckless".
Geoff