You'd have to pick the donkey carefully.
It couldn't just be any old donkey.
So on an Astronaut's checklist:
Pre-Flight Limber-up - Check
Atmospheric Scrubbers - Check
Oxygen Supplies - Check
Auxiliary Supplies - Check
Wonkey Donkey - ...
"Er... Houston we have a problem. {static} we need a better grade of Donkey... {bleep} this one's not going to cut it."