But, those mutations would be incredibly hard to pass through the entire species(unless the species had very, very limited numbers).
I am not sure, but isn't sickle cell anemia more than merely a mutation? Doesn't some environment effect(nutrition, pollution, activity) the developing of sickle cell anemia(or any anemias)? I realize it is genetic, but can't it be found in a person who has no case of this in their family(no genes to cause it)?
Continuing on-most creationists proport that it is ridiculous things can occur with such odds(especially as to the big bang eventually leading to life. Or, some amoeba becoming a human being). However, it is not random, as has been more or less proven(and discussed in this thread over the last few posts). Therefore, under a structured path, it is inevitable(maybe not, but assuming that there will always be some sort of trouble/hardship) that a superior/intelligent life form should emerge, not chance. Also, an interesting concept-they(creationists) say that science shows a temperature difference of 1 K(elvin) at the time of the big bang would end all possibilites of life. But, the big bang is a REPEATING process-Therefore, if it is the wrong temperature, no life for billions of years, it crunches(big crunch theory), and there is another chance at the appropriate temerature. If the chance is missed, another several billion years pass. So, with one in however many billions chance there is of life(and how creationists that this leads to a God, as this chance is, well, infentessimal), there could have been several billion crunch(or, one series of bang to crunch, bound to bang again with a new seires) attempts, leading to the development of life.