If there is any order in the Universe - and we take for granted that there is, or engaging in science makes no sense - then the descriptive and the prescriptive must, ideally, match.
Ought will persistently manage to adapt to the disinterested is of the naturalistic slash quantitative investigation - or find ways to wriggle around it. The physicist can't even live her everyday life in the latter product of experiment and inference; would have to be somewhat clinical or pathological to desire to.
That's part of why empiricism-shaped Anglophone philosophy, in the course of its language "turn", didn't succeed in the early 20th century mission to bury metaphysics. Historically, the latter tended to be the backbone foundation for resting schemes of human matters upon - or at least those that are not an ideological egalitarian surrender. (Latter referring to those supposed and various our minds are so open that our brains have fallen-out stances: "One plan is no more wrong or right than any other"; "everyone is invited to the party, even those who are commanded by their creed to subdue or slay the rest of us"; relativism, etc.).
Even physicalism isn't science. After logical positivism faded away with the original definition, it's become a worldview by the philosopher which attempts to convert aspects and fruit of the naturalistic methodology into a doctrine. Accordingly, there are physicalists somewhere waving their own stash of garlic cloves to ward-off nihilism: Trying to derive an upper, emergent anthropophilic framework from a lower base of uncaring stuff, or extending roots for bits of existing moral/social tradition into it. That is, these recent metaphysicians surely aren't all pitching tents by their gold and silver claims in philosophy of mind territory, or wherever their current hustle and bustle "seems" to be.