The fundamental premise that is the basis of the scientific method and therefore underlies all science:
The natural universe is a closed system [using the layman's definition of that term, not the physicist's], whose behavior can be predicted by theories derived logically from empirical observation of its past and present behavior.
Religion is antiscience because its basis is the hypothesis that an invisible, illogical supernatural universe exists, from which fantastic creatures and incredible forces emerge on random occasions, to perturb the behavior of the natural universe; and because this hypothesis is offered
without evidence of any kind, merely the occasional tortilla (out of billions) with a scorch mark that is said to resemble the face of a person who lived in Biblical times,
of whom no portraits exist against which to compare it.
Because this hypothesis claims to falsify the scientific method (which has been tested exhaustively for half a millennium and never come close to falsification) and therefore
falsify science itself, it clearly qualifies as an
extraordinary assertion.
At this point the Rule of Laplace is automatically invoked:
Extraordinary assertions must be supported by extraordinary evidence before anyone is obliged to treat them with respect.
This rule is fundamental to science, because without it the extremely finite resources of science would be quickly dissipated in formally testing and disproving every bit of crackpottery that is brought to the doors of the academy.
This is why I consistently treat all religion with aggressive disrespect and contempt. Science is under siege.