Well yes, that’s what analgesic drugs do! They specifically target the pain sensing and transmission pathways in either the peripheral or central nervous system (depending on the drug).
It’s unfortunate if analgesics don’t work well for you; I’m sure you’re not alone in that circumstance. A lot of research effort goes into chronic pain relief and new analgesics that are stronger yet non-addictive. Anyway, adrenaline is the body’s temporary pain reliever. I’m not sure if it has any potential utility for sustained pain relief.