Custom Grown Organ Tranplanted!!!!

madanthonywayne

madanthonywayne

Morning in America
Registered Senior Member
In what is the first example of what will, no doubt, ultimately become the standard procedure in organ transplantation, a woman has received a whole organ grown from her own cells! The benefits of this are many. No more organ shortages. Even better, no anti-rejection medications! Since the organ is grown from your own cells, your body doesn't reject it.
A 30-year-old Spanish woman has made medical history by becoming the first patient to receive a whole organ transplant grown using her own cells.

Experts said the development opened a new era in surgery in which the repair of worn-out body parts would be carried out with personally customised replacements.

Claudia Castillo, who lives in Barcelona, underwent the operation to replace her windpipe after tuberculosis had left her with a collapsed lung and unable to breathe.

The bioengineered organ was transplanted into her chest last June at the Hospital Clinic in Barcelona.

Four months later she was able to climb two flights of stairs, go dancing and look after her children – activities that had been impossible before the surgery. Ms Castillo has also crossed a second medical frontier by becoming the first person to receive a whole organ transplant without the need for powerful immunosuppressant drugs.

Doctors overcame the problem of rejection by taking her own stem cells to grow the replacement organ, using a donor trachea (lower windpipe) to provide the mechanical framework. Blood tests have shown no sign of rejection months after the surgery was complete.

Speaking at a press conference in London yesterday, called to announce the results, Professor Martin Birchall, an ear, nose and throat surgeon from the University of Bristol who collaborated on the case, said: "This is just the beginning. I think it will completely transform the way we think about surgery.

"In 20 years' time the commonest surgical operations will be regenerative procedures to replace organs and tissues damaged by disease with autologous [self-grown] tissues and organs from the laboratory. We are on the verge of a new age in surgical care." http://www.independent.co.uk/life-s.../health-news/the-medical-miracle-1024576.html
Click to expand...
 
how long does it take?
what organs can be made using own cells?
what organs/body parts cannot be made using own cells?
what are dangers involved?
how much?
 
s17ugx.jpg
 
draqon said:
how long does it take?
what organs can be made using own cells?
what organs/body parts cannot be made using own cells?
what are dangers involved?
how much?
Click to expand...
If you follow the link and read the whole article, you'll see that right now they can only do "hollow' organs like the esophagus, but they hope to be able to expand that and, one day, custom make any organ.
 
I think this is amazing and we may live long enough to see the time when organs will be grown as needed.

First a black president, now organ farms. When do we get the flying cars?

~String
 
Bladders were being made years ago, this certainly is a next step but complex organs like the heart, kidneys, lungs, etc are still a breakthrough or two away.

Also embryonic stem cell research is still valid and critical to this field.
 
superstring01 said:
First a black president, now organ farms. When do we get the flying cars?

~String
Click to expand...
Guess what?!
Pentagon Clears Flying-Car Project for Takeoff​
Pentagon mad-science division Darpa is helping build thought-controlled robotic limbs, artificial pack mules, real-life laser guns and "kill-proof" soldiers. So it comes as no surprise, really, that the agency is now getting into the flying-car business, too.

Darpa hopes its "Personal Air Vehicle Technology" project, announced yesterday, will ultimately lead to a working prototype of a military-suitable flying car -- a two- or four-passenger vehicle that can "drive on roads" one minute and take off like a helicopter the next. The hybrid machine would be perfect for "urban scouting," casualty evacuation and commando-delivery missions, the agency believes.

Flying cars have been a just-around-the-corner promise for decades, of course. Today, several companies swear that they are just on the verge of manufacturing such machines. Terrafugia claims its folding-wing mini-plane will be ready to deliver by 2009. Pal-V has a three-wheeled gyrocopter thingy. Urban Aeronautics promises to do the whole thing without any wings or rotors at all. And let's not even get into the personal flying saucers.

Darpa says its Cessna-sized combo vehicle should be able to cruise at 60 mph on land, and 150 mph in the air. It should be able to stay aloft for two hours on a tank of fuel. "The challenge," the agency says, "is to define the major components of such a vehicle that would be suitable for military scouting and personnel transport missions, yet are small enough, inexpensive enough, and easy enough to operate that it can be widely used."

To make the flying car work, Darpa believes, makers will have to use "morphing wings" to ease the transition from road to sky; "optimized disk loading" propulsion, "for the combined fly/drive mission"; and strong flight control software. Darpa isn't making an enormous commitment to the flying car, just yet. This is a project aimed at small business; contracts of this type are typically under a million dollars per year. But maybe, with a small Pentagon push, the flying car dream could finally clear the ground. http://blog.wired.com/defense/2008/11/darpas-flying-c.html
Click to expand...
 
Professor Birchall said the technique could initially be extended to growing other hollow organs such as the bowel, bladder and reproductive tract but could later be extended to solid organs including the heart, liver and kidneys.
Click to expand...


Replacement organs grown in vitro with patient-matched cells are a dream of modern medicine and science, and it looks like we’re almost there (to a limited degree). Earlier in the year there were the reports of tissue engineers growing new beating hearts (in rats only at this stage), although that research is not yet at the stage where they can be transplanted.

One thing to bear in mind is that, although they are amazing pieces of tissue, a trachea is just a tube, a heart is just a pump and a bladder is just a bag. These “simple” organs were always going to be the first organs that could be tissue engineered and transplanted. There is a world of difference when we move onto “complex” organs like the liver and kidneys. The liver is both an endocrine and exocrine organ containing an incredibly complex array of many different cell types doing a variety of different physiological functions. It is the major detoxifying organ of the body and produces a huge array of different hormones and compounds. I cannot see anyone being able to tissue engineer a liver any time soon. Likewise with the kidneys.
 
HR, i actually posted a thread on this a week ago. The bladder has already been done, i dont know the exact dates to see which one came first this women or the other one but i do know they grew her a whole bladder and transplanted it.

as you posted they are already growing hearts and experimenting with other organs. However i would have thought the ovious one this would work on is the liver because that will regrow itself naturally. Hence you can have a live donor liver transplant where they just cut yours in half and leave one half in you and stich the other half into the pt
 
Yes, the liver has an amazing regenerative capability. But that procedure suffers from the same problem that all traditional transplant procedures suffer from – the need for a compatible donor and the necessity for the recipient to take immunosuppressant medication for the rest of their life. Many people die on waiting lists for compatible donor organs.

The aim of tissue engineering is to grow necessary organs using patient-matched cells. This removes problem of immune rejection. However, as I said above, to grow a new liver using a patient’s cells is not going to be easy. Tissue engineered hearts will be accomplished long before it is accomplished with livers and kidneys.
 
oh on a side issue, did you hear of the resurchers who have managed to "wash" blood so that it is ALL O- there for eliminating the requirement to cross match before tranfusion or to relie on dwindiling stores of O- blood.

I belive the resurch was done for the millarty because they have the biggest trauma rates but the whole health system could benift
 
Asguard said:
oh on a side issue, did you hear of the resurchers who have managed to "wash" blood so that it is ALL O- there for eliminating the requirement to cross match before tranfusion or to relie on dwindiling stores of O- blood.

I belive the resurch was done for the millarty because they have the biggest trauma rates but the whole health system could benift
Click to expand...

Do you have a link? It sounds very interesting.
 
ops, i was wrong, they cant convert pos to neg so it would be all either O pos or O neg
 
You must log in or register to reply here.
Back
Top