Is it outright cure or just control?
Predisposition is there in diabetics may be of overeating or of insulin resistance in type2. Unless such predisposition is revered, diabetic can't be said as cured.
Cranberries and Cancer Prevention
- Thread starter S.A.M.
- Start date
Is it outright cure or just control?
Predisposition is there in diabetics may be of overeating or of insulin resistance in type2. Unless such predisposition is revered, diabetic can't be said as cured.
You can eat beets which will clean your blood, watermelons to clean your liver, and do not eat any animal with claws or fish without scales and fins. I have read that eating two almonds a day acts as a preventative against cancer. The idea is to lower the intake of toxins and increase your bodys ability to transport them out.
There is cranberry juice for sale that is 100% unsweetened juice. It's tart, but really good. I get it sometimes, but it's about $8 a bottle.
Carcano
Valued Senior Member
I was reading today that cranberries also contain some Resveratrol, which is thought to have anti-cancer properties...although perhaps not in great enough quantity.
But you can buy Resveratrol in capsule form now.
From Wiki:
"Resveratrol interferes with all three stages of carcinogenesis - initiation, promotion and progression. Experiments in cell cultures of varied types and isolated subcellular systems in vitro imply many mechanisms in the pharmacological activity of resveratrol. These mechanisms include modulation of the transcription factor NF-kB, inhibition of the cytochrome P450 isoenzyme CYP1A1 (although this may not be relevant to the CYP1A1-mediated bioactivation of the procarcinogen benzo pyrene, alterations in androgenic actions and expression and activity of cyclooxygenase (COX) enzymes.
Resveratrol was reported effective against neuronal cell dysfunction and cell death, and in theory could help against diseases such as Huntington's disease and Alzheimer's disease. Again, has not yet been tested in humans for any disease.
Research at the Northeastern Ohio Universities College of Medicine and Ohio State University indicate that resveratrol has direct inhibitory action on cardiac fibroblasts and may inhibit the progression of cardiac fibrosis.
Note that resveratrol bioavailability depends on its conjugate forms: glucuronate and sulfonate, despite that most in-vitro studies use the aglycone form of resveratrol ('aglycone' means without a sugar molecule attached, as in the figure in this article).
Cancer Prevention
In some lineages of cancer cell culture, resveratrol has been shown to induce apoptosis, which means it may kill cancer cells. Resveratrol has been shown to induce Fas/Fas ligand mediated apoptosis, p53 and cyclins A, B1 and cyclin-dependent kinases cdk 1 and 2. Resveratrol is also reported to possess antioxidant and anti-angiogenic properties.[citation needed]
Resveratrol is under extensive investigation as a cancer chemopreventive agent.[43]. Indeed, the Chemoprevention Database reports six studies showing that small doses of dietary resveratrol can reduce colon carcinogenesis in rats and mice.
Life extension and anti-aging
Experiments from the Harvard laboratory of David Sinclair (Biologist) published in 2003 the journal Nature demonstrated that resveratrol significantly extends the lifespan of the yeast Saccharomyces cerevisiae. [44] Dr. Sinclair then founded Sirtris Pharmaceuticals to commercialize resveratrol or related compounds as an anti-aging drug.
Later studies showed that resveratrol prolongs the lifespan of the worm Caenorhabditis elegans and the fruit fly Drosophila melanogaster.[citation needed] In 2006, it also extended the maximum lifespan of a short-lived fish, Nothobranchius furzeri, by 59%, and extended its median lifespan by 56%. Also noted were an increase in swimming performance, an increase in cognitive performance (learning tasks), and a lack of neurofibrillary degeneration (found in a control group). The authors observed that "[resveratrol's] supplementation with food extends vertebrate lifespan and delays motor and cognitive age-related decline could be of high relevance for the prevention of aging-related diseases in the human population."[45] Later in 2006, a report in the journal Nature by Sinclair's laboratory showed that the compound improves health and survival of mice on a high-calorie diet[46].
The mechanisms of resveratrol's apparent effects on life extension are not fully understood, but they appear to mimic several of the biochemical effects of calorie restriction. This seems to function by means of lipase inhibition, reducing the absorption of fat through intestinal walls. A new report indicates that resveratrol activates SIRT1 and PGC-1α and improve functioning of the mitochondria [47].
Only the "Trans" form of the molecule is capable of activating the mammalian SIRT1 gene in vitro; this is also the form predominantly found in red grape skins and red wine. Red grapes grown in some regions (such as New York state) often have much higher concentrations of resveratrol based on the cooler climate and the resulting increase in fungal attacks that promote resveratrol production. However, the amount in any wine, including Muscadine grape wines, is negligible compared to the amount that in theory is needed for health benefits: 1-10 milligrams per liter of wine versus hundreds to thousands of milligrams/day."
But you can buy Resveratrol in capsule form now.
From Wiki:
"Resveratrol interferes with all three stages of carcinogenesis - initiation, promotion and progression. Experiments in cell cultures of varied types and isolated subcellular systems in vitro imply many mechanisms in the pharmacological activity of resveratrol. These mechanisms include modulation of the transcription factor NF-kB, inhibition of the cytochrome P450 isoenzyme CYP1A1 (although this may not be relevant to the CYP1A1-mediated bioactivation of the procarcinogen benzo pyrene, alterations in androgenic actions and expression and activity of cyclooxygenase (COX) enzymes.
Resveratrol was reported effective against neuronal cell dysfunction and cell death, and in theory could help against diseases such as Huntington's disease and Alzheimer's disease. Again, has not yet been tested in humans for any disease.
Research at the Northeastern Ohio Universities College of Medicine and Ohio State University indicate that resveratrol has direct inhibitory action on cardiac fibroblasts and may inhibit the progression of cardiac fibrosis.
Note that resveratrol bioavailability depends on its conjugate forms: glucuronate and sulfonate, despite that most in-vitro studies use the aglycone form of resveratrol ('aglycone' means without a sugar molecule attached, as in the figure in this article).
Cancer Prevention
In some lineages of cancer cell culture, resveratrol has been shown to induce apoptosis, which means it may kill cancer cells. Resveratrol has been shown to induce Fas/Fas ligand mediated apoptosis, p53 and cyclins A, B1 and cyclin-dependent kinases cdk 1 and 2. Resveratrol is also reported to possess antioxidant and anti-angiogenic properties.[citation needed]
Resveratrol is under extensive investigation as a cancer chemopreventive agent.[43]. Indeed, the Chemoprevention Database reports six studies showing that small doses of dietary resveratrol can reduce colon carcinogenesis in rats and mice.
Life extension and anti-aging
Experiments from the Harvard laboratory of David Sinclair (Biologist) published in 2003 the journal Nature demonstrated that resveratrol significantly extends the lifespan of the yeast Saccharomyces cerevisiae. [44] Dr. Sinclair then founded Sirtris Pharmaceuticals to commercialize resveratrol or related compounds as an anti-aging drug.
Later studies showed that resveratrol prolongs the lifespan of the worm Caenorhabditis elegans and the fruit fly Drosophila melanogaster.[citation needed] In 2006, it also extended the maximum lifespan of a short-lived fish, Nothobranchius furzeri, by 59%, and extended its median lifespan by 56%. Also noted were an increase in swimming performance, an increase in cognitive performance (learning tasks), and a lack of neurofibrillary degeneration (found in a control group). The authors observed that "[resveratrol's] supplementation with food extends vertebrate lifespan and delays motor and cognitive age-related decline could be of high relevance for the prevention of aging-related diseases in the human population."[45] Later in 2006, a report in the journal Nature by Sinclair's laboratory showed that the compound improves health and survival of mice on a high-calorie diet[46].
The mechanisms of resveratrol's apparent effects on life extension are not fully understood, but they appear to mimic several of the biochemical effects of calorie restriction. This seems to function by means of lipase inhibition, reducing the absorption of fat through intestinal walls. A new report indicates that resveratrol activates SIRT1 and PGC-1α and improve functioning of the mitochondria [47].
Only the "Trans" form of the molecule is capable of activating the mammalian SIRT1 gene in vitro; this is also the form predominantly found in red grape skins and red wine. Red grapes grown in some regions (such as New York state) often have much higher concentrations of resveratrol based on the cooler climate and the resulting increase in fungal attacks that promote resveratrol production. However, the amount in any wine, including Muscadine grape wines, is negligible compared to the amount that in theory is needed for health benefits: 1-10 milligrams per liter of wine versus hundreds to thousands of milligrams/day."
John Connellan
Valued Senior Member
Yes, it should be called reversatol
