Antibiotic resistance, evolution and public policy

And? How does that support denying adaptation? Remember, he said, "evolved bacterial resistance to antibiotics is referred to as "adaptation" which is 99% incorrect." Even if the terms are used interchangeably, that would simply make his assertion self-contradictory, as it would then also be claiming that referring to it as "evolution" is "99% incorrect."

Easy to denigrate when people who tout science can't be bothered to understand what they're trying to use as a cudgel, and others who will flock to their defense as a knee-jerk reaction, without even bothering to see if they flubbed the science.

So, do you agree with billvon that referring to it as "adaptation" is "99% incorrect"? o_O

Or are you just defending a political ally, science be damned? o_O

You can give the stink-eye all you want :p

Billvon is, however, correct - the issue at hand (and what is causing issues with antibiotic resistance) is not the adaptation portion (which refers to singular or small groups of a sample) but the continued evolution towards resistance on the whole. Adaptation implies the bacteria becoming resistant after being in contact with the antibiotic - evolved resistance means the bacteria is already resistant to it.

Per his post, which you have so desperately twisted into a pretzel to try and discredit him (attacking the person much?):
Correct. Adaptation is the response of an organism to the environment. A bacteria that thickens its cell membrane in response to a more hostile environment is an example of adaptation. Evolution is a genetic (i.e. preserved) change in the phenotype of an organism, caused by mutation and natural selection.

Unfortunately, in an attempt to be politically correct, evolved bacterial resistance to antibiotics is referred to as "adaptation" which is 99% incorrect. The problem is not that single organisms BECOME resistant, the problem is that populations of organisms EVOLVE resistance over time. But since the anti-science right wing abhors the use of the term "evolution" the incorrect term "adaptation" has become common, and is now misleading people to think that the problem of antibiotic resistance is a temporary one, awaiting only a way to overcome an adaptation response that all bacteria show to antibiotics.

And as a result, people are dying.

Ergo, what he said is correct - adaptation is the response of an/the organism. Evolution is a genetic change.

The interesting part, Syne, is your dishonesty in all this... as you are the one that said:
Can you cite a source supporting the notion that resistant strains of a bacteria are indeed different bacteria species? If not, then you can only be talking about adaptation. You do realize that not all evolution is adaptation, right? o_O

Your claim, in that post, is that Billvon is claiming resistant strains of bacteria (such as Staphylococcus aureus) are different species of bacteria. He never made such a claim. What he stated, and what anyone who isn't operating on an agenda can read, is that certain anti-science groups hate the word "evolution" because they do not believe in "evolution", and so the word "adaptation" has been thrown around instead, despite being technically incorrect in this context.

Additionally, I do not see anything in Billvon's post "denying adaptation", as you claim:
he was outright denying adaptation

At no point did he "deny adaptation" - he merely (correctly) pointed out the fact that adaptation and evolution are not one and the same, despite the terms being used almost interchangeably (much the same as the evidence I provided should have shown you):

http://evolution.berkeley.edu/evolibrary/article/misconcep_06
ust as it is tempting to take natural selection to extremes, it is tempting to look for the evolutionary advantage of any trait of an organism — in other words, to see adaptations everywhere. Of course, the natural world is full of adaptations — but it is also full of traits that are not adaptations, and recognizing this is important. However, before we examine traits that are not adaptations, it will be useful to specifically define what an adaptation actually is and how we can determine whether or not a trait qualifies as an adaptation.

https://www.quora.com/What-is-the-difference-between-evolution-and-adaptation
Elijah Williams, Undergraduate Zoology Major
Written Aug 9, 2016

Evolution can be defines as the change in the allelic frequencies within the gene pool of a population. The term “adaptation” is typically used to describe a newly mutated trait that increases fitness in a particular environment. This will lead to the alleles for that trait becoming more frequent throughout the population. In theory (assuming a dominant recessive relationship between two alleles), the more “fit” allele will go to fixation (every individual will have it) and the other will go extinct altogether given an infinite amount of time. In reality though the less fit alleles often manage to scrape by if they aren’t too harmful.

While adaptation usually refers to new traits, I think it can also refer to the natural selection of variations of existing traits. If you have a population that contains white rabbits and black rabbits and move the whole population into the tundra, the white fur could be considered an adaptation that gives those rabbits an advantage over the black ones even though it did not recently mutate into the gene pool. However most people just use adaptation to refer to traits that become frequent in response to the current environment(e.g. white fur is an adaptation to winter snow in temperate forests, not the tundra) so you are probably fine just using it that way. Basically an adaptation is just any beneficial trait and whether or not a trait is beneficial is dependent entirely on the environment. Evolution is the process by which that beneficial traits spreads throughout a population.

https://www.merriam-webster.com/dictionary/adaptation
3: adjustment to environmental conditions: such as a : adjustment of a sense organ to the intensity or quality of stimulationb : modification of an organism or its parts that makes it more fit for existence under the conditions of its environment

https://www.merriam-webster.com/dictionary/evolution
4a : descent with modification from preexisting species : cumulative inherited change in a population of organisms through time leading to the appearance of new forms : the process by which new species or populations of living things develop from preexisting forms through successive generations <Evolution is a process of continuous branching and diversification from common trunks. This pattern of irreversible separation gives life's history its basic directionality. — Stephen Jay Gould>; also : the scientific theory explaining the appearance of new species and varieties through the action of various biological mechanisms (such as natural selection, genetic mutation or drift, and hybridization) <Since 1950, developments in molecular biology have had a growing influence on the theory of evolution. — Nature> <In Darwinian evolution, the basic mechanism is genetic mutation, followed by selection of the organisms most likely to survive. — Pamela Weintraub>b : the historical development of a biological group (such as a race or species) : phylogeny

Now, that is not to say that adaptations do not, over generations, lead to evolution

At this point, Syne, your intentional dishonesty is in full display for all to see... I would say you should be ashamed of yourself, but, heh, at this point, we know well that you have no such shame...

The simple point is this - Billvon stated that some groups despise the word evolution and deny that evolution exists (macroevolution in general). You challenged him to provide evidence of this, which he did... and then you started on this tangent that he somehow "denies adaptation exists". His claim that saying "adaptation" in place of "evolution" is incorrect is, at the simplest level, absolutely correct - if species of bacteria did not "evolve" resistance, but only "adapted" resistance, then there would be no problem - the adapted bacteria would eventually die out and that would be that. Evolved resistance, due to passing of genes down (such as in the case of E.Coli, which I believe a study by Richard Lenski showed, actually "developed" an entirely new gene!)
 
Evolution is not intelligent design. There is no "towards" anything. Failed adaptations evolve, and even persist (if not too detrimental), just like successful ones.
If something heads to a certain point, through design or otherwise, it is quite correct to say that it is heading "towards" that thing.
If bacteria does not become resistant to that which it is in contact and can kill it, it will die out.
Evolution, by default, is toward resistance in such scenarios.
Either the bacteria resists and survives (evolution), or it dies out.
This needs no intelligent design.
There is no critical mass of adaptations in a population that suddenly go from adaptation to evolution. You're arguing a difference without a distinction, while I'm pointing out the error in making such a distinction.
Is not adaptation simply the arrival of a (beneficial) change / mutation within part of the populace, while evolution is the process by which that change affects every member of the populace?
As such there does seem to be a clear distinction.
 
Is not adaptation simply the arrival of a (beneficial) change / mutation within part of the populace, while evolution is the process by which that change affects every member of the populace?
As such there does seem to be a clear distinction.

I think the whole issue can be summed up by stating a test claim:

"The ability for an organism to adapt to change, is one that continuously evolves"

Then draw your definitions from that.

The words "adaptation" and "evolution" are two separate categories and trying to compare them as if in the same category is silly IMO

Adaptation is a part of the definition of Evolution

Like oxygen is to Earth's atmosphere IMO

see category mistake
 
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So far, I'm the only one of the two of us who's provided any definitions at all, and all those have come from reputable sources (which you've yet to even attempt to refute...other than perhaps by bare assertion alone). I guess you think you're fooling someone, but I can guarantee you, the only people you are fooling is people like you, pretending to be smart while remaining ignorant of science.

Again, I am always glad when people like you consider me a fool. It would be akin to a KKK member calling me a racist. That sort of criticism I can live with.

So insult away, and keep trying to push political correct terminology over science!
 
In evolution, we only know where something was "heading" in hindsight. There is no predicting, nor guiding, without direct genetic manipulation, aside from trivial epigenetic changes due to lifestyle choices, etc.. "Towards" and "heading" are human conceptions grafted onto mindless evolution.
Indeed, but they are conceptions that we can apply where it is appropriate.
It is appropriate to refer to the evolution of bacteria toward resistance.
That the term was applied due to hindsight is not in question.
No, adaptation leads to resistance, because adaptation is defined as promoting survival fitness.
Adaptation leads to resistance of only part of the population that adapts.
For the population as a whole to survive it must evolve such that the population retains that adaptation.
If it doesn't, the population eventually dies off.
It is the process of evolution that takes it from adaptation to being part of the base nature of the organism.
Now whether that adaptation becomes widespread is a competition between a variety of adaptive traits. Evolution can equally lead to mutations that are not beneficial but are still inheritable due to being minimally detrimental. For example, vestigial structures are not adaptations, although they could have been at one time, but they persist because they do not negatively impact organism survival and reproduction significantly.
Whether evolution can equally lead to non-beneficial mutations, that it is not limited in applicability to adaptation, is irrelevant.
The process by which adaptation moves from the part to whole is evolution.
Please stop arguing irrelevancies.
Yeah, you just quoted me as saying, "Evolution is not intelligent design."
I am making the point that no-one ever implied intelligent design, thus your reference to it was irrelevant.
No. Evolution is the process that includes adaptation. Evolution requires adaptation but adaptation does not entail evolution.
Strictly speaking, evolution is a process that includes adaptation.
Otherwise you are simply stating the obvious and trying to make it seem as though you're correcting someone.
You're not.
If evolution were defined as "the process by which that change affects every member of the populace" adaptation would be something distinct from the process of evolution...when in actuality it's required for evolution.
Adaptation IS distinct from the process of evolution.
Whether adaptation is required for evolution or not does not mean that there is no distinction between the two.
It is recognisably different, the very definition of distinct.
An egg is required for an omelette - are you trying to say there is no distinction between an egg and an omelette?
There is a distinction, but it's not the one billvon and Kitt are trying to make.
So now you say there is a distinction?
Please make up your mind.
 
I think the whole issue can be summed up by stating a test claim:

"The ability for an organism to adapt to change, is one that continuously evolves"
I don't think this is strictly true, in that an adaptation that does not get passed on will not result in evolution.
I think it more likely that an organism that is able to adapt more readily will likely evolve more.
But that's just me thinking out loud.
Then draw your definitions from that.

The words "adaptation" and "evolution" are two separate categories and trying to compare them as if in the same category is silly IMO

Adaptation is a part of the definition of Evolution

Like oxygen is to Earth's atmosphere IMO

see category mistake
Are you suggesting we can not compare oxygen to the Earth's atmosphere? ;)

I think a better analogy would be between oxygen and oxidisation, although even then it's possibly not too good.
With yours, you're saying that evolution simply includes adaptation among many other discrete things, that together make up evolution, whereas my understanding is that evolution requires adaptation, and is how an adaptation spreads to the entire populace (even if that involves the unadapted population dying off).

But then I believe you can have a non-evolutionary adaptation - a short-term adaptation that never develops into an evolution of the whole.
Not sure you can have oxidation without oxygen, though. :)
 
I don't think this is strictly true, in that an adaptation that does not get passed on will not result in evolution.
I think it more likely that an organism that is able to adapt more readily will likely evolve more.
But that's just me thinking out loud.
Are you suggesting we can not compare oxygen to the Earth's atmosphere? ;)

I think a better analogy would be between oxygen and oxidisation, although even then it's possibly not too good.
With yours, you're saying that evolution simply includes adaptation among many other discrete things, that together make up evolution, whereas my understanding is that evolution requires adaptation, and is how an adaptation spreads to the entire populace (even if that involves the unadapted population dying off).

But then I believe you can have a non-evolutionary adaptation - a short-term adaptation that never develops into an evolution of the whole.
Not sure you can have oxidation without oxygen, though. :)
another thread perhaps?
 
*chuckles* Syne has himself twisted up in more knots than an Auntie Anna's Pretzel with his dishonesty and twisting of words... this is actually quite entertaining!

Since most of your post is useless posturing and attempting to twist even more, I'll simply address your elephant in the room:
Straw man. I never made any such claim, and I challenge you to quote where I did. o_O

Easy:

Can you cite a source supporting the notion that resistant strains of a bacteria are indeed different bacteria species? If not, then you can only be talking about adaptation. You do realize that not all evolution is adaptation, right? o_O

Your own words Syne. You made the claim that Billvon somehow said that resistant strains are somehow different species - a false claim, and one you used in an attempt to use a strawman to discredit him.

If you wish to claim that was NOT the intent of your post, then by all means - explain what you actually meant - it should be entertaining to listen to someone OTHER than Trump lie through their teeth :)
 
The simple point is this - Billvon stated that some groups despise the word evolution and deny that evolution exists (macroevolution in general). You challenged him to provide evidence of this, which he did... and then you started on this tangent that he somehow "denies adaptation exists". His claim that saying "adaptation" in place of "evolution" is incorrect is, at the simplest level, absolutely correct - if species of bacteria did not "evolve" resistance, but only "adapted" resistance, then there would be no problem - the adapted bacteria would eventually die out and that would be that. Evolved resistance, due to passing of genes down (such as in the case of E.Coli, which I believe a study by Richard Lenski showed, actually "developed" an entirely new gene!)

Yep. And the political desire to use less accurate words to avoid attack by the right is driving the use of those words, resulting in a less-educated populace more likely to believe dangerously inaccurate science. It helps the right wing consolidate power, but ultimately hurts us all.
=================
Evolution by Any Other Name: Antibiotic Resistance and Avoidance of the E-Word
http://dx.doi.org/10.1371/journal.pbio.0050030

Citation: Antonovics J, Abbate JL, Baker CH, Daley D, Hood ME, Jenkins CE, et al. (2007) Evolution by Any Other Name: Antibiotic Resistance and Avoidance of the E-Word. PLoS Biol 5(2): e30. doi:10.1371/journal.pbio.0050030


The increase in resistance of human pathogens to antimicrobial agents is one of the best-documented examples of evolution in action at the present time, and because it has direct life-and-death consequences, it provides the strongest rationale for teaching evolutionary biology as a rigorous science in high school biology curricula, universities, and medical schools. In spite of the importance of antimicrobial resistance, we show that the actual word “evolution” is rarely used in the papers describing this research. Instead, antimicrobial resistance is said to “emerge,” “arise,” or “spread” rather than “evolve.” Moreover, we show that the failure to use the word “evolution” by the scientific community may have a direct impact on the public perception of the importance of evolutionary biology in our everyday lives.
=============
 
The increase in resistance of human pathogens to antimicrobial agents is one of the best-documented examples of evolution in action at the present time, and because it has direct life-and-death consequences, it provides the strongest rationale for teaching evolutionary biology as a rigorous science in high school biology curricula, universities, and medical schools. In spite of the importance of antimicrobial resistance, we show that the actual word “evolution” is rarely used in the papers describing this research. Instead, antimicrobial resistance is said to “emerge,” “arise,” or “spread” rather than “evolve.” Moreover, we show that the failure to use the word “evolution” by the scientific community may have a direct impact on the public perception of the importance of evolutionary biology in our everyday lives.

Shakespeare is correct ' A rose by any other name would smell as sweet '

Antimicrobial resistance which
“emerges”
“arises”
“spreads”
“evolves”

end up the same, microbes which resist antibiotics killing them

Personally microbes which resist my attempts to kill them before they kill me scares the brown stuff out of me

I don't care what you call how resistance happens

“emerge”
“arise”
“spread”
“evolve”

it will still be the same brown stuff coming out

re·sist
\ri-ˈzist\
  • : to fight against (something) : to try to stop or prevent (something)
  • : to remain strong against the force or effect of (something) : to not be affected or harmed by (something)
  • : to prevent yourself from doing something that you want to do
Full Definition

  • intransitive verb
  • : to exert force in opposition
    transitive verb
  • 1 : to exert oneself so as to counteract or defeat <he resistedtemptation>
  • 2 : to withstand the force or effect of <material that resists heat>
    synonyms see oppose
Origin: Middle English, from Anglo-French or Latin; Anglo-French resister,from Latin resistere, from re- + sistere to take a stand; akin to Latinstare to stand — more at stand.
First use: 14th century
Synonyms: buck, defy, fight, oppose, repel, withstand
Antonyms: bow (to), capitulate (to), give in (to), knuckle under (to), stoop (to), submit (to), succumb (to), surrender (to), yield (to)

Mirriam-Webster

:)
 
I don't care what you call how resistance happens
You probably should. If it's short term adaptation, then overuse of antibiotics is a temporary problem. If it's evolution, then the problem is going to continue to get worse.

But that's not politically correct, so it's important to always call it "adaptation" or you will be attacked and ridiculed.
 
You probably should. If it's short term adaptation, then overuse of antibiotics is a temporary problem. If it's evolution, then the problem is going to continue to get worse.

But that's not politically correct, so it's important to always call it "adaptation" or you will be attacked and ridiculed.

You missed the larger picture

I don't care what you call how it happens

It happens

so it's important to always call it "adaptation" or you will be attacked and ridiculed

???? Are you serious???

Are you saying I have to call it adaption to be politically correct?

The bug knows if I am being politically correct or not which affects the bugs reaction to antibiotics?

If it's short term adaptation, then overuse of antibiotics is a temporary problem

That does not compute and as someone remarked it's so far beyond wrong it's not even computed as wrong

:)
 
You missed the larger picture

I don't care what you call how it happens

It happens

so it's important to always call it "adaptation" or you will be attacked and ridiculed

???? Are you serious???

Are you saying I have to call it adaption to be politically correct?

The bug knows if I am being politically correct or not which affects the bugs reaction to antibiotics?

If it's short term adaptation, then overuse of antibiotics is a temporary problem

That does not compute and as someone remarked it's so far beyond wrong it's not even computed as wrong

:)

The irony, here, is that you and Billvon are arguing for the same side - call it what you will, it is happening. The problem is that certain circles (especially in the bible belt) so incredibly abhor the word "evolution" that they will refuse to believe ANYTHING that even mentions the term.
 
The irony, here, is that you and Billvon are arguing for the same side - call it what you will, it is happening. The problem is that certain circles (especially in the bible belt) so incredibly abhor the word "evolution" that they will refuse to believe ANYTHING that even mentions the term.

If I was a doctor and had a patient who abhorred evolution I would whisper to him, as I handed him a packet of sugar pill placebos,

' You have a super bug which has evolved to destroy your life force and the only way to save your life is to religiously take this medication which will reverse the evolution '

Not ethical but heaps of fun

Sorry god

:)
 
If I was a doctor and had a patient who abhorred evolution I would whisper to him, as I handed him a packet of sugar pill placebos,

' You have a super bug which has evolved to destroy your life force and the only way to save your life is to religiously take this medication which will reverse the evolution '

Not ethical but heaps of fun

Sorry god

:)

At one time, I'd have done the same...

But after reading, time and again, how these fuckwits have allowed their own CHILDREN to die from perfectly curable conditions because they believe in "faith healing" and denounce modern medicine as "the work of the devil"... I'm just sick of it. Hell, we've had dozens of children the last five years or so die in Pennsylvania alone because of this bullshit... I cannot believe, in this day and age where information is so readily available, that parents would be so willfully negligent as to let their child wither away and die because of treatable conditions:
http://www.pennlive.com/news/2017/02/2-year-old_dies_after_faith_st.html
A Berks County couple who told police their faith forbids them from seeking medical treatment has been charged in the recent death of their 2-year-old daughter, according to an Associated Press report.

Jonathan and Grace Foster of Upper Tulpehocken Township were charged Wednesday with involuntary manslaughter and child endangerment in the Nov. 8 pneumonia death of their daughter, Ella Grace, becoming the latest members of their sect charged for not taking a dying child to a doctor, the report said.

The Fosters, members of Mechanicsburg-based Faith Tabernacle church, attributed the toddler's death to "God's will," according to charges filed in the case.





















The Fosters, who have six other young children, were released on unsecured bail, the report said. Berks County District Attorney John Adams said the couple has agreed to take their children to doctors when they are sick. Child welfare officials are monitoring the family.

The Fosters told police their church does not believe in any medical treatment whatsoever, charging documents state.

Let that sink in... they "do not believe in ANY medical treatment"... what the flying FUCK?
 
You missed the larger picture. . . I don't care what you call how it happens It happens
OK.
so it's important to always call it "adaptation" or you will be attacked and ridiculed
???? Are you serious???
Are you saying I have to call it adaption to be politically correct?

Yes, often you will. That's why scientists who publish papers on such things use "evolution" less and less, as the article I referenced demonstrates. Because there are people out there who will refuse to read anything with the word "evolution" in there, and will react angrily to anyone who uses it.
The bug knows if I am being politically correct or not which affects the bugs reaction to antibiotics?
Nope, it could care less.
If it's short term adaptation, then overuse of antibiotics is a temporary problem
That does not compute and as someone remarked it's so far beyond wrong it's not even computed as wrong
Sorry you don't understand it.
 
they believe in "faith healing"

Agree unbelievable

Could you streach ' faith healing ' for the kids by concocting some sort of mumbo jumbo with a few ' our lord ' thrown in and ' holy water '?

Just for the kids

Let the adult go and aim for a Darwin Award

Kids put into welfare after parents buried

Sad world

:frown:
 
antibiotic resistance always starts with adaptation

Only a Sith speaks in absolutes...

Can you provide evidence that antibiotic resistance cannot POSSIBLY start any other way (such as, through random mutation, lucky survival due to incomplete antibiotic regimen, etc)?

Also, knock it off with the persistent red herrings - it is a well known fact that people deny evolution, and will decry anything with the word in it (fuck, it's also well known that people will disregard modern medicine in favor of "faith healing" and allow their kids to die because of it) - so, yeah... you've rather lost that tangent already.
 
I couldn't think of a better example of survival of the fittest as the evolution of antibacterial resistant microbes.

Yay evolution...................go for it guys

Yay science:
My recent coworker is working on developing/breeding phages to replace antibiotics given to cattle and swine.
I read somewhere that a goat herd was training his goats to prefer to eat invasive vegetation eliminating the need for herbicides.
 
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