Using the CRISPR/Cas9 gene editing technique, scientists at Temple University eliminated HIV-1 DNA from T cell genomes in lab experiments, and prevented reinfection after the cells were re-exposed to the virus, they report in a study.
The CRISPR/Cas9 gene editing method uses guide RNA proteins to alter targeted sections of DNA in a cell. Previously, scientists at Temple had edited HIV DNA out of human cell lines. The new study, using patient cells grown in the lab, showed cleared cells were no longer susceptible to infection by HIV.
http://www.upi.com/Health_News/2016...m-genome-of-human-immune-cells/1511458583664/
Paper: http://www.nature.com/articles/srep22555
The CRISPR/Cas9 gene editing method uses guide RNA proteins to alter targeted sections of DNA in a cell. Previously, scientists at Temple had edited HIV DNA out of human cell lines. The new study, using patient cells grown in the lab, showed cleared cells were no longer susceptible to infection by HIV.
http://www.upi.com/Health_News/2016...m-genome-of-human-immune-cells/1511458583664/
Paper: http://www.nature.com/articles/srep22555