Schizophrenia, Adrenochrome and Cancer

V

visceral_instinct

Monkey see, monkey denigrate
Valued Senior Member
This is pretty fascinating.

http://www.ncbi.nlm.nih.gov/pubmed/14975514

http://www.yourhealthbase.com/database/a109d.htm

Drs. Hoffer and Foster now propose that schizophrenia is associated with high blood levels of the hallucinogen adrenochrome, which is formed by oxidation of adrenaline (epinephrine). The low antioxidant status of schizophrenics worsens their condition because they are unable to prevent the oxidation. The excessive conversion of adrenaline to adrenochrome tends to make schizophrenic patients adrenaline deficient. This in turn may explain why they tend to smoke more – nicotine increases adrenaline turnover in the brain. Thus smoking may actually be a form of self-medication.
Dr. Hoffer has had excellent results by treating schizophrenics with high doses of niacin (vitamin B3) and ubiquinone (coenzyme Q10) which both lower elevated adrenochrome levels.
To explain the abnormally low cancer rates among schizophrenia patients Drs. Hoffer and Foster suggest that elevated adrenochrome levels may protect against tumor development. Parnate, an antidepressant, encourages adrenochrome production and has halted at least one case of brain cancer.
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For those who don't like long and complicated explanations, what the evidence seems to suggest is that schizophrenia is caused by too-high adrenochrome, or oxidized adrenalin. This substance though seems to prevent cancers forming.

There was a drug developed which utilized this action of adrenochrome, but from what I can find on Google, this stuff wasn't approved for use for some reason.

Matrix Pharmaceuticals Inc. has received a US patent covering the composition of IntraDose Injectable Gel. This gel contains cisplatin and epinephrine (adrenaline) and is designed to be injected directly into tumour masses. Cisplatin is a very powerful oxidant which will almost certainly rapidly convert the adrenaline to adrenochrome. While the manufacturers of IntraDose consider cisplatin to be the active cytotoxic agent in IntraDose, it seems more likely that adrenochrome and its derivatives may, in fact, be more effective. IntraDose gel has undergone or is undergoing a series of Phase III open-label clinical studies, being injected into patients’ tumours that have been identified as the most troublesome by their physicians. The results have been impressive for breast cancer, malignant melanoma, esophageal cancer and cancer of the head, neck and liver.
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