red blood cell

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People loving in high altitude have red blood cell the same size as people who live at the sea level ?


What happen to the nucleus of the red blood cells ?

Do Mammals and fish have same size red blood cell ?
 
Yes, but people at Hugh altitude have. MORE Red blood cells

Red blood cells don't have a nucleus
 
RBC never had a nucleus, they are constructed in the bone marrow without one.
 
RBC never had a nucleus, they are constructed in the bone marrow without one.

Hey pal we have learned something from the site . I knew there was something odd about the rbc, There are some more odd things about RBC. like what does mitochondria is doing ?
 
RBC never had a nucleus, they are constructed in the bone marrow without one.

Err no, the immature cells have a nucleous and divide like any other normal cell. Its only once they become an adult cell that the nucleous edjected and the cell moves into the blood stream and become what everyone thinks of as an RBC
 
Hey pal we have learned something from the site . I knew there was something odd about the rbc, There are some more odd things about RBC. like what does mitochondria is doing ?

In mammals, erythrocytes also lose all other cellular organelles such as their mitochondria, Golgi apparatus and endoplasmic reticulum.

As a result of not containing mitochondria, these cells use none of the oxygen they transport; instead they produce the energy carrier ATP by the glycolysis of glucose and lactic acid fermentation on the resulting pyruvate.

A true mutant of the evolved kind.
 
That leaves only this question:

People loving in high altitude have red blood cell the same size as people who live at the sea level ?

There is a train that goes up the Andes. The indigenous people who board this train will carry a small flask with a rod, and a pouch of coca leaves. When they reach a certain elevation, they chew the leaf, spit it into the flask, and stir and mash it with the rod. At some point they add baking soda, and produce a paste which they paint onto their gums. When the train arrives several miles high, and they exit into the sun, you will notice how red they have become. They seem to move around without labored breathing, while the occasional traveler is ashen, bent over and seeing stars.

Before trains, it would have taken them perhaps a couple of days to make the climb. Probably that would be enough time to adjust.

My thinking is that the size of the blood cell may not matter, since the issue is how to develop a sufficient partial pressure - in each direction - to ensure gas transport across the alveolar membrane. It's more a pressure gradient problem than anything else.
 
RBC never had a nucleus, they are constructed in the bone marrow without one.

No (as has already been said). Only in the final stages of erythrocyte development is the nucleus expelled.

bloodweb.jpg
 
People loving in high altitude have red blood cell the same size as people who live at the sea level ?


What happen to the nucleus of the red blood cells ?

Do Mammals and fish have same size red blood cell ?

Where do you get that from?
 
Where do you get that from?

I read the ant eater have different size red corpuscles , So that create a question since the ant eater is a mammal what about fish and since people a high altitude have less oxygen, How is the carrier affected (RBC )
 
I read the ant eater have different size red corpuscles , So that create a question since the ant eater is a mammal what about fish and since people a high altitude have less oxygen, How is the carrier affected (RBC )

If you say ant eater is a mammal, what about lizard ( reptile) that also eats ants?
 
Red blood cells also show that the nucleus (DNA) is not necessary to be alive. However, the loss of the DNA will restrict their ability to replicate.

On the other hand, the nucleus which is expelled is neither alive nor can it replicate. It is more like a virus.This simple observation suggests that the cell body is the living part of the cell (retained in RBC), while the nucleus/DNA is more like a viral hard drive, which experiments have shown, can be swapped out, as long as the cell body is viable.
 
Another consideration comes from an engineering design POV. The nucleus uses a lot of energy for RNA synthesis and transport. This energy requirement is compounded by all the support that goes along with this such as synthesis on the mRNA at the ribosomes. By eliminating the nucleus, energy is freed up, which creates an internal chemical potential for energy diversion.

Picture a supply of water going into a manifold. The loss the nucleus sort of closes some of the big valves, so we get more pressure within the remaining hoses in the manifold. The RBC need to exchange O2/CO2, without the nucleus we have more energy for the membrane.
 
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