Ionizing radiation, such as gamma rays, X-rays and radioactive particles can cause cancer by damaging DNA. However, how this happens, or how many tumors are caused by radiation damage has not been known.
Previous work on cancer had revealed that DNA damage often leaves a molecular fingerprint, known as a mutational signature, on the genome of a cancer cell. The researchers looked for mutational signatures in 12 patients with secondary radiation-associated tumors, comparing these with 319 that had not been exposed to radiation.
https://www.mdtmag.com/article/2016...=5574494&et_rid=%%subscriberid%%&location=top
Previous work on cancer had revealed that DNA damage often leaves a molecular fingerprint, known as a mutational signature, on the genome of a cancer cell. The researchers looked for mutational signatures in 12 patients with secondary radiation-associated tumors, comparing these with 319 that had not been exposed to radiation.
https://www.mdtmag.com/article/2016...=5574494&et_rid=%%subscriberid%%&location=top