Questions about Insulin

K

Kumar

Registered Senior Member
Hello,

I have folowing questions about insulin--natural and injected:-

1. What is the difference between natural & injected insulin(endogenous & exogenous) in their chemistry & effects? Whether chemical & structural formula of both are same & if yes, how these effect differently?

2. Is it true: "Injected insulin is more likely to disapate as it should in the proper times because its not resistant like a diabetic Type2's impaired insulin." Means, whether natural insulin in type2 is impaired due to IR, whereas injected insulin is not & therefore is effective? Whether injected insulin doesn't cause insulin resistence whereas oral insulin promoting medicines can?

3. Excess insulin in blood can mean "hyperinsulinemia" & it can be a common condition in type2 with IR patients. Will a diabetic patient get complications related to "hyperinsulinemia" or not, as his insulin levels may remain always in excess? This excess insulin can be due to natural reasons with out medications AND by medications---Natural; prediabetes, type2 with IR, Medicated; insulin promoting medicines & injected insulin.


My main question is that, whether injected insulin can cause or add to insulin resistence or not AND whether oral insulin promoting medicines can cause or add to IR or not?

Best wishes.
 
These question were mentioned in simple language, but can be based on bit dynamic thoughts. Anyway pls tell me:-

Can insulin & c-peptide tests tell every stage of diabetes in folowing considerations?

When person on no medications: Insulin test & C-peptide tests can tell our insulin in blood. If excess, it can indicate IR, if low then type2/IDDM. When on medicines/insulin: C-peptide can tell our insulin & Insulin test can tell total insulin. Elevated C-peptide here can mean IR whereas lower- type2/IDDM. Insulin test will tell total Insulin including injected one, if elevated can tell hyperinsulinemia.

It it correct?
 
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