Pulmonary Interstitial Fibrosis(Lung Disease)

P

plakhapate

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My wife (age 51) detected above disease in October 2006.

She gets tired after climbing even 10 steps of staircase.

Doctor gave Steroids, which gave lot of side effects.

Now we have slowly stopped steroid treatment.

Allopathic doctor said there is no specific treatment and involves trial and error.

Now we have started Ayurvedic medicine.

Doctor says curing a disease is a slow process and may take more than one year.

Is there any sure shot medicine and involves quick recovery.

Pls share your experience.

P.J.LAKHAPATE
plakhapate@rediffmail.com
 
lung transplantation

High doses of oral corticosteroids (e.g., prednisone) are the usual treatment. Cytotoxic drugs such as cyclophosphamide and azathioprine have also been used. The response to corticosteroids is better in patients with more inflammation and less fibrosis noted on lung biopsy. Lung transplantation has been suggested for selected patients with end-stage pulmonary fibrosis. The outlook for recovery is generally poor for occupational dust diseases and idiopathic (no-known cause) interstitial pulmonary fibrosis in which the lungs progressively stiffen.
 
If you stick with Ayurvedic medicine I think you'll find its benefits outweigh those of conventional medicine. This is a type of practive that's been used for a very long time in India, they have tried many things and determined which help to relieve and prevent / cure illnesses. I myself find they usually give a great deal of energy, calmness, and help with the condition. If you continue following this there's no telling what sort of progress might be made. I certainly think this is the best choice for you.
 
Recently in Australia it is found that the presence of Gasoline vapours in atmosphere provoks the Pulmonary Interstitial Fibrosis if it is in the initial stage.

If this is true, then the gas pollution may be the reason for provoking the disease of my wife because we stayed in Andheri (Mumbai suburb) for 2 months in conjested area where vehicular pollution is very high.

After knowing this reason , is there any medicine available for curing this disease?

Pls share your experience.

P.J.LAKHAPATE
plakhapate@rediffmail.com
 
Pulmonary Fibrosis - Pranaayam

Dear Mr. P.J.LAKHAPATE,

I gone through your message, my wife (age 43 yrs) is also sufferring from Pulmonary Fibrosis. I dont want to make much comment about the medicines but I am sure if Yogas/ Pranaayaam & Various Breathing Excercises may help a lot to your wife.


I will also welcome for any suggestions in this matter.

Ravi Kabra.
 
Pulmonary Interstitial Fibrosis

Mr. Ravi Kabra,
Pls let me know your contact details.
See your personal email also.
P.J.LAKHAPATE
M-9867069587
R-91-22-27702655
 
IVE HEARD TALK OF SOME CHEAP DRUG BEING TESTED...

i heard it on anther thread..

a cure for cancer... since cancer cells use a different, oxygen starved form of metabolism.... that.. this drugs.. turns on mitocondria and stuff and thus... allows cancer cells to use oxygen, which then causes the messed up cancer cells to simply die.

if this is true...

the pharmicuticals will never tell you.. since they cannot make money off of it... as the drug is cheap.

i cant remember the thread... it had links to a news story.

-MT
 
the pharmicuticals will never tell you.. since they cannot make money off of it... as the drug is cheap.
Click to expand...
Of course they can make money. The cheaper it is to produce the higher the profit. They'll just charge what the market will bear.
 
The only treatment with documented effect in the endstage of the disease is oxygen and lung transplantation............
 
Oli said:
Of course they can make money. The cheaper it is to produce the higher the profit. They'll just charge what the market will bear.
Click to expand...

no... this particular drug... is so cheap... there would be no money to be made... but cancer could be cured... and it would cost the consumer about as much as an asprin.

i wish i could remember the links or thread.

-MT
 
no... this particular drug... is so cheap... there would be no money to be made... but cancer could be cured... and it would cost the consumer about as much as an asprin.
Click to expand...
And by that logic then, no-one would make aspirin because it's too cheap to make a profit on...
From the link:
The pay-off is that if DCA does work, it will be easy to manufacture and dirt cheap.
Click to expand...
So there are intentions to manufacture, if the drug actually works.
 
plakhapate said:
My wife (age 51) detected above disease in October 2006....Pls share your experience....
Click to expand...
I own stock in:
Discovery Laboratories, Inc. Quoting from their PR of about a year ago: It "is developing its proprietary surfactant technology as Surfactant Replacement Therapies (SRT) for respiratory diseases. Few or no approved non-animal derived surfactants are available. Discovery's proprietary SRT is also being developed in an aerosolized form under the name Aerosurf(TM), for neonatal respiratory disorders. Discovery is preparing to conduct Phase 2 pilot studies with Aerosurf(TM), aerosolized SRT administered through nasal continuous positive airway pressure (nCPAP). Also for premature infants, Discovery concluded a Phase 2 trial of Surfaxin for Bronchopulmonary Dysplasia (BPD), also known as Chronic Lung Disease. Discovery and announced preliminary results of a Phase 2 trial to address Acute Respiratory Distress Syndrome (ARDS) in adults, and is developing aerosol to potentially address Acute Lung Injury (ALI), cystic fibrosis and other respiratory conditions."

DSCO, their stock symbol, is possibly the world's expert on non-cancer lung disease.
You might want to ask them, or at least visit www.discoverylabs.com

They have nothing on the market yet. - They would have except for some very bad luck. - of the hundreds of stability batches that were stable, one of the three designated as a "registration batch" was not stable for the full year. Stock fell dramatically and I bought some as if patient, it will do every well.

On comments about drug being to cheap to make - that is silly you just price it at a profit level. I also own stock in BARR & TEVA, two of the largest generic drug makers. They both, especially BARR, are making patent challenges every month to try to get right to sell drugs more cheaply than current patent holder. I do not own any "big pharma" but they have bought up some of the small early stage drug developers I did own, at large profits to me.
 
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plakhapate said:
Billy T,
Can you explain what is Surfactant Replacement Therapies (SRT)?
I am a Chemical Engr, so I will understand if you explain.
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You probably know more than me. DiscoveryLab's is a complex mix of about 8 agents (why they had some problems in meeting the year stability tests, I think) As I under stand it a "surfactant" is sort of a detergent. I am sure you know more than I do. Visit their web site, I gave it earlier. See especailly their discussion (if it is still available) of why the FDA's stability test failed. (Terrible bad luck as only one, but it was one of the three batches designated to FDA, among many dozens failed. This cost them months of investigation and has delayed comercialization by more than a year. - Millions of dollars lost, not to mention the deaths of many babies it would have saved.)
 
At Fareynght's link you will find:

"...Published in the March issue of the journal Chest, the research shows that more than half of the patients treated with Viagra, also known medically as Sildenafil, improved their walking distance by at least 20 percent during a standard test to measure lung function.

"Over five million worldwide suffer from this devastating disease, so we are hopeful that this drug may prove an effective therapy for pulmonary fibrosis," said the study's principal investigator, Dr. David A. Zisman, medical director of UCLA's Interstitial Lung Disease Program and assistant professor of pulmonary and critical care medicine at the David Geffen School of Medicine at UCLA. Many patients with pulmonary fibrosis also have pulmonary hypertension, which constricts arteries and lessens blood flow to the lungs, resulting in diminished lung capacity and breathing difficulties. According to Zisman, Sildenafil may help breathing by opening or dilating blood vessels to allow more blood flow to the lungs.

In this pilot study, 14 idiopathic pulmonary fibrosis patients initially took a standard six-minute walking test. All patients were then given oral Sildenafil therapy for three months, followed by a second walking test to gauge performance changes. Researchers noted that 57 percent of the patients improved their walking distance by 20 percent or more. The average improvement in walking distance was 49 meters (161 feet). ..."

I am not sure, but think viagra basically increases the NO (or is it NO2 ?) in the blood. As the lungs are specaized for the exchange of gases with the blood, I would serieously look into which it is and then consider having her breadth air with a little of this "viagra gas" mixed in. Could start with low % and increase while monitoring for side effects. (Google "laughing gas" also as either NO or NO2 was extensively used by dentists years ago with only side effect being light headedness and inclination to laugh.)
 
Now my wife has started Pranayam (3 times a day).

This include Kapalbhati , Uddai, Bhastrika asanas.

A tremendous improvement is seen in one month.

Earlier she could not even walk 50 steps.

Now she can walk to and fro two kilometer per day without much problem.

Now climbing the stairecase is also not a big problem.

However it is a long way to go for further improvements.

Any suggestions for faster recovery.

P.J.LAKHAPATE
plakhapate@rediffmail.com
 
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