It appears that mitochondria...the once bacteria and now an essential powerhouse of the cell refuse to go into Apoptosis and activate an efficient energy saving mechanism of NAD+ production when cells are not over nourished. And this is the reason why people who eat a bit of food live longer.
A more concise explanation of this phenomenon can be found here:
http://www.medicalnewstoday.com/articles/83268.php
Quoting:
So we can make a molecule that activates these genes responsible for mitochondria efficient energy cycle...and thus prolongue cell life.
A more concise explanation of this phenomenon can be found here:
http://www.medicalnewstoday.com/articles/83268.php
Quoting:
researchers in this latest study have discovered two mammalian genes called SIRT3 and SIRT4 that are directly involved in prolonging cell life.
So we can make a molecule that activates these genes responsible for mitochondria efficient energy cycle...and thus prolongue cell life.