The statement is really broad that ends up tying it all together, that our troubles are never just heaped solely on us, that we all have something to gripe about, yet in the end, it doesn't matter. The frogs were, to me, a way of giving this idea substance, a giant metaphor, and certainly a christian one.
I found Julliane Moore's character to be the most interesting; rarely ever do I see that role...the gold-digger who ends up falling in love with her husband before he dies. Because, of course, his death was the one thing she married him for.
Of course...the music adds a lot. Aimee Mann's music is always great...but 'It's Not Going To Stop' is just perfect for the movie.