Researchers at The Ohio State University are working on a new way to treat drug-resistant cancer using unusual method - a Trojan horse, made of DNA that hides the invading force, which in this case, is a common cancer drug.
In laboratory tests, leukemia cells that had become resistant to the drug absorbed it and died when the drug was hidden in a capsule made of folded up DNA.
Previously, other research groups have used the same packaging technique, known as "DNA origami," to foil drug resistance in solid tumors. This is the first time researchers have shown that the same technique works on drug-resistant leukemia cells.
http://www.eurekalert.org/pub_releases/2016-02/osu-dh022316.php
Paper: http://onlinelibrary.wiley.com/doi/10.1002/smll.201670014/abstract
In laboratory tests, leukemia cells that had become resistant to the drug absorbed it and died when the drug was hidden in a capsule made of folded up DNA.
Previously, other research groups have used the same packaging technique, known as "DNA origami," to foil drug resistance in solid tumors. This is the first time researchers have shown that the same technique works on drug-resistant leukemia cells.
http://www.eurekalert.org/pub_releases/2016-02/osu-dh022316.php
Paper: http://onlinelibrary.wiley.com/doi/10.1002/smll.201670014/abstract