...joining this discussion now:
SILICIUM BASED LIFE:
Well the Silicium atom has - like Carbon - 4 possibilities to bind with other atoms, thus (theoretical) ability to form long chains, and cycles... However the CHON (Carbon Hydrogen Oxygen Nitrogen) based life is much much more probable:
First C, H, O and N are very frequent elements in the universe, while the next line of the Mendeleiev table is much less frequent.
Second The electronic orbitals around Si are such that it favours ionic-type links, which means: less flexibility, cristalline structure, too strong links. Good example is CO2, very important element in life, a gas at normal temperature and pressure, bringing greenhouse effect capabilities (yes it can help...), while SiO2 is a cristal (harder to incorporate in oxydizing/reducing type of chemical reactions)
Third you need a solvent: the CHON solvent is H2O, water - liquid between 0°C and 100°C... While it would be NH3 - liquid at much lower temperatures... which means the cinetics of chemical reactions are much much slower...
In summary, not impossible, but quite improbable to have a non Carbon-based life.
ENANTIOMERES:
the life is Left-handed on Earth... and there is quite some mystery re. the explanation... nobody knows... however I've read a recent article (pb is I absolutely do not remember on which Internet site !!!) on a discovery that in some far molecular interstellar cloud, there was UV light that was polarized, and the polarization triggered a preference for L-shaped molecules or D-shaped depending on this polarization.
My (personal) hypothesis is thus that we are L-shaped because the UV light (the one that can trigger reactions binding prebiotic molecules in interstellar cold clouds) in our neighborhood was polarized in a certain way..
No reason why in some other area of the galaxy, one finds D-shaped life...
HUMAN-LIKE LIFE FORM?
For me, yes for the general aspect like: organs performing sensing would be dual (it gives a 3-d perception), with probably sesnsitivity to the light (CHON-life, thus general conditions close to Earth-conditions, thus atmosphere with Oxygen - the most efficient oxidizer for Redox reactions, energy pumps...-, protection against hard radiation, some CO2, N2, possibly Sulphur-derivatives... ), in any case transparency to visible light, next UV, next IR. Definitely some symmetry axis, a sensitivity to gravity separating the top from the bottom, with sensors rather at the top etc....
Now details may be quite different. Could be fun to imagine a complete history of an exoplanet, then retrace how the life could evolve (with same fundamentals as earth as I just mentionned... DNA and so on..) and 'create' an alien form, both close and different from us...
INTELLIGENCE?
Well, no idea. Drake equation and my personal belief say Yes... but maybe not frequent, and nearly impossible to contact, unless we are extremely lucky (and that does not prevent us to try... see SETI).
Scorpio